Ib tug loj npaum li cas ntawm buffers yuav tsum tau nyob rau hauv downstream purification txheej txheem ntawm biopharmaceuticals. Qhov raug thiab rov tsim dua tshiab ntawm cov buffers muaj kev cuam tshuam zoo rau cov txheej txheem purification protein. Kev sib xyaw hauv online thiab kev siv tshuaj online tuaj yeem ua ke ntau yam ntawm cov khoom sib xyaw ua ke. Niam cawv thiab cov diluent sib xyaw hauv online kom tau txais cov phiaj xwm daws teeb meem. Cov khoom yog raws li kev paub txog kev tshawb fawb, thiab qhov zoo yog los ntawm lub tswv yim ntawm kev tsim (QbD). Los ntawm lub sijhawm tiag tiag hauv online (Real in time) saib xyuas thiab tswj ntawm ob qhov ntsuas tshuaj, cov yam ntxwv tseem ceeb (CQA) ntawm cov khoom (CQA), pH thiab conductivity thaum lub sij hawm tsim khoom, xyuas kom muab cov buffers ruaj khov thiab zoo ib yam. zoo rau cov txheej txheem downstream los pab biopharmaceutical tuam txhab uas muag 'parameter tso tawm lub hom phiaj. Cov txheej txheem kev npaj ua kua ib txwm xav tau ntau lub tso tsheb hlau luam thiab ntim loj. IVEN nqa cov neeg siv khoom lag luam tshiab kev paub dhau los, txo cov hneev taw ntawm qhov tsis siv tshuaj hauv cov txheej txheem huv, thiab txo qis kev nqis peev ua ntej thiab tom qab tsim khoom thiab cov nqi khiav lag luam. , Txhim kho kev tsim khoom, xyuas kom meej cov txheej txheem tseem ceeb (CPP) ntawm qhov tsis zoo thiab nws cov traceability, thiab thaum kawg txhim kho cov tshuaj zoo.